Vice President JD Vance said Tuesday that an emerging nuclear agreement with Iran would be a “home run for the American people,” even if Israel objected, as President Trump predicted a deal could be finalized within days.

Speaking to Fox News, Vance acknowledged that US and Israeli interests do not always align, particularly on Iran. “The United States’ main objective is to ensure that Iran does not have a nuclear weapon,” he said, framing the deal as fundamentally an American priority rather than a regional one.

Vance argued that the Trump administration had created negotiating conditions superior to those of the 2015 Obama-era deal, which Trump exited in 2018 partly at Netanyahu’s urging. The key improvement, Vance said, would be a rigorous inspections regime to verify Iranian compliance over the long term.

“We’re going to accomplish the president’s mission, but verify over the long term that the Iranians are keeping their end of the bargain,” he said.

The comments came one day after Iran and Israel exchanged their first direct strikes since April, rattling the negotiations before both sides agreed to stand down. Trump denied that Netanyahu had defied him by ordering a retaliatory strike, saying that by the time he spoke with the prime minister, Israeli forces were already in motion. “If I tell him to do something, he does it,” Trump told the BBC.

Trump told reporters Tuesday that the deal, which he said would prohibit nuclear weapons “in any shape or form” and reopen the Strait of Hormuz, could be signed within two or three days, though he added it could theoretically be concluded “in one hour, if you want to know the truth.”

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